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Showing posts with label Drugs. Show all posts
Showing posts with label Drugs. Show all posts

Saturday, March 01, 2014

Use and Abuse of (shhh) 'Drugs!'

People outside of the UK may not know about Professor David Nutt, who was government Chief Advisor in the UK for ten years, and was finally sacked for not coming to the conclusions that they wanted him to.   He explains it all in the first few minutes of this 50 minute presentation.



He's very good on the way the discussion of legal and illegal drugs blurs the more important measures of the amount of harm to self and others of drug abuse - for instance how much worse for people and society alcohol proves to be (and we are talking about evidence here, not BS).


I recommend this whole presentation, which covers the legal situation which prevents proper scientific work on drugs which can be abused, or simply used for recreation, but which also have exciting therapeutic possibilities, from MDMA to LSD, these things need to be available at least to researchers. Currently, when he invents new combinations to reproduce the effects, the substance immediately gets made illegal.

"People cannot be rational when something's illegal. And that's why we have to be very, very cautious, about making anything illegal."
Prof Nutt.


The chart that he and his team created for the UK, comparing the relative risks of a range of drugs, appears irrefutable (it has been independently reproduced by European colleagues).


And I was intrigued by his suggestion that with enough research he could create something that would let you feel intoxicated for the evening, then take the antidote, sober up immediately, and feel OK to drive home, and wake up without a hangover the following day.  Breaking news.

"I’ve done the prototype experiments myself many years ago, where I’ve been inebriated and then it’s been reversed by the antagonist. There’s no question that you can produce a whole range of effects like alcohol by manipulating the brain.”

Wednesday, January 11, 2012

a life well lived

Albert Hofmann would have reached his 106th birthday today.

Astonishingly, he actually did celebrate his 102nd birthday, fit and healthy (as you can see here).

Because of his 'problem child' dominating his reputation, we may forget that he had a long career as a research scientist, and, according to this site

"His interest in synthesizing LSD involved a search for a stimulant that would help as a medicine for circulatory and respiratory illnesses."

"His work there led to numerous other discoveries including Hydergine, a medicine for improving circulation and cerebral function, and Dihydergot, a circulation and blood pressure stabilizing medicine."

So you could attribute his longevity to the spiritual peace and cheerfulness that he acquired from experimenting on himself - with the Hydergine and Dihydergot.  ;-)

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If you want to do something to mark the day, you might consider writing to Casey 'Freeblood' Hardison, sending him some stamps, or money.   



Drug Equality Alliance


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Today also marks the fifth anniversary of the death of Robert Anton Wilson (aged 74), and D.E. Harding (aged 97 - the "On Having No Head" author) - who contrived to die within hours of each other, on Albert's birthday.

Robert Anton Wilson week starts, over at Boing-Boing

Wednesday, April 16, 2008

Bike Day


Actually, some people consider the 19th as Bike Day, but what the hey...

AH: “Last Friday, April 16, 1943, I was forced to interrupt my work in the laboratory in the middle of the afternoon and proceed home, being affected by a remarkable restlessness, combined with a slight dizziness. At home I lay down and sank into a not unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring); I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away.”






From Bruce Eisner's Vision Thing: Three days later, on April 19, 1943 at 4:20 PM, Hofmann took the first planned trip. He took what he thought would be the smallest amount that would be noticeable - which was 250 micrograms or about one four thousandth of a gram.
AH: "By now it was already clear to me that LSD had been the cause of the remarkable experience of the previous Friday,for the altered perceptions were of the same type as before, only much more intense. I had to struggle to speak intelligibly. I asked my laboratory assistant, who was informed of the self-experiment, to escort me home. We went by bicycle, no automobile being available because of wartime restrictions on their use. On the way home, my condition began to assume threatening forms. Everything in my field of vision wavered and was distorted as if seen in a curved mirror. I also had the sensation of being unable to move from the spot. Nevertheless, my assistant later told me that we had traveled very rapidly. Finally, we arrived at home safe and sound."









Albert in German



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Bonzi on a bike

Friday, January 11, 2008

Happy 102nd Birthday, Uncle Albert!

Albert Hofmann two years ago, at age 100 Today I'd prefer to celebrate the living first, so wish Albert Hofmann a very happy 102nd birthday. If anyone could offer a better image for the sensible use of psychedelic substances, then he seems like living proof that (generally) they can prove life-enhancing.

Sadly, he lost his wife, Anita Hofmann-Guanella, on December 20th 2007, at the age of 94 - and they had shared lives for an amazing 75 years...
Anita and Albert on his 100th birthday
I don't wish to appear a zealot (nothing I can think of suits everybody), and I also don't feel like discussing the stupid image of jumping out of a window (whoops, I put that image in your head yet again!) As Bill Hicks said, if you think you can fly, why don't you take off from the ground, you don't see pigeons taking the lift (elevator) to the sixth floor, now do you?

That drugs can confuse, mislead, upset or disturb some people seems obvious to me. For some reason (worth studying) many people don't find it obvious that alcohol (for instance) appears in a multitude of anti-social or self-damaging behaviours, and yet appears encouraged (even among fitness fanatics like sports people, who always seem to get rewarded with champagne). That they spray it rather than drink it might seem wise (driving fast cars, precision kicking of a ball, etc) but the image remains of alcohol as a reward! Alcohol as a celebration (Christmas).

Nothing wrong with a wee drop of wine when you reach 100 At the same time - of all the drugs, alcohol represents the longest and clearest experiment to prove that Prohibition doesn't work. It simply led to badly made, or badly measured, use of moonshine - it brought crime, greed, violence, furtiveness and other nasty stuff into existence - and it poured money into criminal families like the Kennedy family, who went on to ill-fated attempts at power. Whether the assassinations came from religious nonsense (anti-Catholic), or old scores from the crime wars, or something else, I will leave to better researchers than myself.

Prohibition Didn't Work

For me the most interesting (or curious) result of Prohibition failing was that the same tactic was immediately turned on other substances. My private theory remains that a department of the police existed, and no-one wanted to simply throw them out of work (bureaucracy seems self-perpetuating) so they simply turned their focus on a drug less popular with journalists, lawyers, judges, politicians, etc. They looked around and found marijuana getting used by Mexicans and Blacks (and some bohemian artists) and turned the full force of the same tactics onto that. And we still live with that locked-in bit of non-sense (if it didn't work with alcohol, who in their right mind thought it might work on something else?)

During alcohol prohibition, of course, you could legally smoke dope...

A Personal Opinion

I have extended rants on this matter, which I won't bore you with now. A chief of police in the UK recently recommended legalizing all drugs, and I agree. They may still need licensing and controlling, researching and measuring, but at least people would receive clear dosage levels, quality controlled, and (hopefully) also receive a good education on the use and misuse of drugs.

As people only ever talk (vaguely) about Abuse (never Use) they keep the demonizing factor going, yet may happily receive morphine from a nurse when in pain. (Use).

And pain expresses itself through the bodymind, so we can't only talk of physical pain, as psychological/psychic/emotional pain hurts just as bad.
Robert Anton Wilson
This poor police chief now finds himself howled down by a few individuals, just for trying to act in a rational manner, because a few children died after taking something someone gave them as 'ecstasy'. No-one knows what chemicals they actually took (illegal supply), no-one knows what dose they took (illegal supply), and no-one educated these children about the difference between considered use and abuse - or gave them any pointers - just surrounded the whole subject with paranoia, and made their friends too scared to call emergency services (criminal involvement), or to tell the doctors the truth (even if they knew which chemical the victim had taken, it's strength, purity, etc.)

(Never show any hint of the positive when discussing 'drugs', or as Bob so astutely pointed out -'some drugs' - and please don't discuss them in a rational manner).

And into those journalistic manipulations of distressed parents (for whom I have the greatest sympathy at the loss of a child), very few people mention the much greater damage, death, illness, unhappiness, etc caused by (say) alcohol, to unstable (or ill-informed) individuals and society.

Enough, already. My three glasses of red wine, and one tobacco roll-up may have tired me slightly, so I'll find another time and place for this.

We MLA students also want to mark the first anniversary of a planet without Robert Anton Wilson - but with something positive (our Wiki project, amongst other things), and little sadness. Whatever your belief about afterlives (and mine tends towards 'dead' people continuing in other people's minds and memories - especially if they have left books or buildings, ideas or discoveries), I miss him still.

Bob wrote simply and clearly about 'death', and elsewhere you can find his lucid use of words - in Cheerful Thoughts on Death and Dying. I leave you to explore, because 1:30 a.m. (GMT) means I gotta walk the dog one more time, and go to bed.

Peace to all sentient beings.

Wednesday, April 18, 2007

Things to say BEFORE you die

It probably comes as no surprise that quite a lot of people who enjoy the MLA also smoke (or have smoked) either grass or hash. Even today, it can prove ill-advised to admit to it in certain careers, and Lenny Bruce got it wrong predicting that it would become legal within a few years (he spoke in the early 60s) because "all the law students I know smoke it." He didn't realise just how hard 'They' would beat us all up in the later Sixties, and ever since - and how cowardly the dope-smokers who wanted to become lawyers, politicians, journalists, film stars, etc - let alone parents, school-teachers, policemen (even) would mostly prove. Rock musicians seem the bold and brave exception. Oh and people demanding Hemp as a medicine (possibly one of the oldest medicinally used plants on the planet). Well, now someone tells me that Carl Sagan liked a smoke. I'd missed that.

According to Wiki:

Carl Sagan was an avid user of marijuana, although he never admitted this publicly during his life. Under the pseudonym "Mr. X", he wrote an essay concerning cannabis smoking in the 1971 book Marihuana Reconsidered, whose editor was Lester Grinspoon. In his essay, Sagan commented that marijuana encouraged some of his works and enhanced experiences. After Sagan's death, Grinspoon disclosed this to Sagan's biographer, Keay Davidson. When the biography, entitled Carl Sagan: A Life, was published in 1999, the marijuana exposure stirred some media attention (quickly forgotten). I had read Grinspoon years back, but didn't much worry who hid behind the mask of Mr X. It could so easily have hidden a creative scientist in just about any field...

I'd like to produce in evidence someone my mum loved (and she hated dope-smoking). I can do it because he has left the planet, and because, before leaving, he decided to declare his love in his own words. Louis Armstrong. You can read a whole bunch of his own words here, under Pot Smoker of the Month.
But more relevant to the whole damned stupid story of wasted money in pursuit of a victimless crime (and if I could grow my own I wouldn't come in touch with either criminals or hard drugs) - in the light of recent new estimates of the harm that different drugs do to individuals and society [1] - I would like to quote a chunk from this website (and I hope they'll forgive me - but I just know a lot of people don't click through on links - and they put the case so clearly!) These lucid and sane words come fromKeith Halderman: Louis Armstrong and Marijuana an Anecdote [2]

In his recent biography Laurence Bergreen summed up Armstrong’s relationship with the drug; "He loved marijuana too. He smoked it in vast quantities from his early twenties until the end of his life; wrote songs in praise of it; and persuaded his musician friends to smoke it when they played. He planned to call an unpublished sequel to his autobiography Gage, his pet name for marijuana, but once his manager found out about the title and the subject of the work, he suppressed the manuscript, trying to protect Louis's reputation. Sections of the work that survived the censorship show that he regarded it as an essential element in his life and beneficial to his health." (from Louis Armstrong: An Extravagant Life, page 4) Armstrong maintained marijuana to be a thousand times better than whiskey and that it relaxed him while also keeping him clear headed. He pointed out that, though he smoked marijuana, during the entire forty-five years he had been blowing trumpet he had never let his public down, claiming that they had a reverence for each other. [...]

The arguments against marijuana have drastically changed over time. During the 1920s and 1930s, when prohibition came about, reform groups and government officials strenuously maintained that marijuana caused it users to become violent and that long term use led to inevitable insanity. After World War II the primary rationale for keeping marijuana illegal became the "stepping stone" or "gateway" theory, the idea that smoking pot caused the use of harder more hazardous drugs. A common modern day point of view on the drug is presented in the following paragraph from the online encyclopedia Encarta's entry on marijuana; "Negative effects of marijuana use can include confusion, acute panic reactions, anxiety attacks, fear, a sense of helplessness, and loss of self-control. Chronic marijuana users may develop amotivational syndrome characterized by passivity, decreased motivation, and preoccupation with taking drugs. Like alcohol intoxication, marijuana intoxication impairs judgment, comprehension, memory, speech, problem-solving ability, reaction time, and driving skills." Contemporary charges also include a propensity towards lung disease and depression in users.[...]
Although he operated in an often violent milieu, which included the honky tonks of New Orleans and mafia owned venues in Chicago and New York, there is no record of Armstrong committing violent acts himself, no arrests, no charges of domestic violence from his ex-wives. As for insanity he contended that he "always had a sane mind from the day he was born." [...]
The notion that marijuana leads to the use of more problematic drugs also finds no support from the life of Louis Armstrong. Easily available heroin and cocaine held no interest for him and Armstrong never used them. [...]
Armstrong eluded amotivational syndrome too, in fact, a fair description of him might include the word workaholic. He composed dozens of jazz standards, recorded over a thousand songs, averaged more than 300 concert dates per year, toured much of the world for the State Department, had parts in thirty plus films, became ubiquitous on radio and television, and found time to write two autobiographies, more than ten magazine articles, hundreds of pages of memoirs, and thousands of letters. He kept up this strenuous pace well into his sixties.

He worked so hard because he enjoyed it, as he enjoyed life in general. No confusion, acute panic reactions, anxiety attacks, fear, a sense of helplessness, and loss of self-control plagued Louis Armstrong. He often commented on how good life had been to him.

Marijuana did not affect Armstrong’s memory, he carried literally thousands of tunes in his head. It did not impair his judgment, comprehension, or problem solving ability when it came to his career, he earned the accolades of the world as well as financial security. His speech in the form of scat singing has influenced vocalists ever since it was first heard. As for reaction time, it was an essential element of his genius. The improvisional nature of jazz required quick and innovative reactions and Louis Armstrong was the master.

Louis Armstrong's biography reveals no automobile accidents. It does, however, disclose a remarkable set of lungs. A consensus of jazz critics consider recordings he made for Okeh records in 1925 under the name Louis Armstrong and his Hot Five then later Hot Seven to be among the finest in jazz history, with his ability to hit the high notes especially remarkable. No one with lungs impaired by marijuana smoking would have been able play that music. Yet, Armstrong reported that some specific songs were laid down after he and the band had smoked, the implication being that this was the usual practice. One of the tunes named "Muggles" was a synonym for marijuana. Armstrong continued to play and record until the very last year of his life, with plans for more music when his health recovered. He died of heart disease, one of the few illnesses that the government has not yet tried to link to, as Armstrong would put it, that beautiful gage.

In his book Chocolate to Morphine Dr. Andrew Weil correctly contends that, "Any drug can be used successfully, no matter how bad its reputation, and any drug can be abused, no matter how accepted it is. There are no good or bad drugs; there are only good and bad relationships with drugs." The evidence is clear, Louis Armstrong had a very good relationship with marijuana and we are all the better for it.



So finally, in his own words:

As we always used to say, gage is more of a medicine than a dope. But with all the riggermaroo going on, no one can do anything about it. After all, the vipers during my haydays are way up there in age - too old to suffer those drastic penalties. So we had to put it down. But if we all get as old as Methuselah our memories will always be of lots of beauty and warmth from gage. Well, that was my life and I don't feel ashamed at all. Mary Warner, honey, you sure was good and I enjoyed you 'heep much'. But the price got a little too high to pay (law wise). At first you was a 'misdemeanor'. But as the years rolled on you lost your misdo and got meanor and meanor. (Jailhousely speaking).
Sooo "Bye Bye, I'll have to put you down, Dearest."
[signed] `Soul Foodly, Satchmo'.

[1]Professor Nutt and his team analysed the evidence of harm caused by 20 drugs including heroin, cocaine, cannabis, ecstasy, LSD and tobacco.

They asked a group of 29 consultant psychiatrists who specialise in addiction to rate the drugs in nine categories. Three of these related to physical harm, three to the likelihood of addiction and three to social harms such as healthcare costs. The team also extended the analysis to another group of 16 experts spanning several fields including chemistry, pharmacology, psychiatry, forensics, police and legal services.

The final rankings placed heroin and cocaine as the most dangerous of the 20 drugs. Alcohol was fifth, the class C drug ketamine sixth and tobacco was in ninth place, just behind amphetamine or "speed".

Cannabis was 11th, while LSD and ecstasy were 14th and 18th respectively. The rankings do take into account new evidence that specially cultivated "skunk" varieties of cannabis available now are two to three times stronger than traditional cannabis resin. [NB: 2-3 times seems modest, as the media often amp that up to 25 times stronger - such hysteria seems best countered with Ben Goldacre's Bad Science column

To get their scare figure, The Independent have compared the worst cannabis from the past with the best cannabis of today. But you could have cooked the books in exactly the same way 30 years ago if you’d wanted: in 1975 the weakest herbal cannabis analysed was 0.2%; in 1978 the strongest herbal cannabis was 12%. Oh my god: in just 3 years herbal cannabis has become 60 times stronger.

And in fact, what’s most amazing is that this scare isn’t new. In the US, in the mid 1980s, during Reagan’s “war on drugs”, it was claimed that cannabis was 14 times stronger than in 1970, which rather sets you thinking. If it was 14 times stronger in 1986 than in 1970, and it’s 25 times stronger today than the beginning of the 1990s, does that mean it is now, in fact, 350 times stronger than 1970?

That’s not even a crystal in a plant pot. That’s impossible.

[2] Source: Trebach Report (3-29-06)
[Keith Halderman is a research assistant at the Trebach Institute and is working on his Ph.D at American University. His is a member of the Liberty and Power group blog at HNN.]

Excuse me, I have to stop now, as it sounds as though someone is kicking down my front door for the fourth time in my life... (the others happened back in the Sixties when the Notting Hill police station had a famously corrupt guy in charge). And I don't even have any weed! (sigh) Back then it wouldn't have mattered, as they often brought their own to plant on you...